金沙集团

陈碧峰

发布时间:2019.01.21 10:06

陈碧峰

副教授、硕士生导师

基本情况

出生年月:1984.07

最高学位:博士

Email:cbifeng@jshagroup.com 


教育及工作经历

2002.09-2006.07,云南师范大学,生命科学金沙集团 ,生物技术专业,学士学位;

2006.09-2009.07,云南大学,生命科学金沙集团 ,遗传学专业,硕士学位;

2011.09-2014.08,香港中文大学,生物医学金沙集团 ,生物医学研究方向,博士学位。

2009.09-2010.04,上海第二军医大学,医学遗传学教研室,研究助理(Research Assistant);

2010.07-2011.03,湖北省医学会临床外科杂志编辑部,编辑(Editor)。


研究领域及主要成果

研究专长及研究技术:人类重大遗传疾病与候选基因的关联研究(SNP genotyping),以及候选基因的功能研究(Screening rare mutation);癌症的表观遗传学研究(miRNA, DNA methylation, and other epigenetic modifications)。

研究兴趣:探寻候选基因与疾病之间的易感性,阐述候选基因在疾病的发生过程中的作用机制,以及从表观遗传学的角度来探究癌症发生发展过程中,小RNA分子(microRNA)和DNA甲基化(DNA methylation)等表观遗传学手段在其中的作用


代表性论文、专著和专利等(不超过10项)

1. Tang L, Wan P, Wang Y, Pan J, Wang Y, Chen B. Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population.Inflamm Res. 2015; 64(10):817-24. (Corresponding author; IF=2.347) 

2. Lu Li*, Bi-Feng Chen* and Wai-Yee Chan. An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1). Int J Mol Sci. 2015 Mar; 16(3): 5125–5140. (*Co-first Author; IF=2.862) 

3.Wang Y, Tang L, Pan J, Li J, Zhang Q, Chen B. The recessive model of MRP2 G1249A polymorphism decrease the risk of drug-resistant in Asian Epilepsy: a systematic review and meta-analysis. Epilepsy Res. 2015;112:56-63. (Corresponding author; IF=2.015) 

4. Chen BF, Suen YK, Gu S, Li L, Chan WY. A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor. Scientific Reports. 2014; 4:6413. (IF=5.078) 

5. Bi-Feng Chenand Wai-Yee Chan: The de novo DNA methyltransferase DNMT3A in development and cancer. Epigenetics: official journal of the DNA Methylation Society. 2014; 9 (5):     669-77. (IF=5.108) 

6. Chen BF, Gu S, Suen YK, Li L, Chan WY.MicroRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer. Epigenetics: official journal of the DNA Methylation Society 2014; 9(1):119-128. (IF=5.108) 

7.Liang Tang, Yan Wang,Bifeng Chen: A variant within intron 1 of PTPN22 gene decreases the geneticsusceptibility of Ankylosing Spondylitis in central south Chinese Han population. Scand J Rheumatol. 2014; 43(5):380-384. (Corresponding author; IF=2.607) 

8.Liang Tang*, Bifeng Chen*, Bo Ma, Shengjie Nie: The Association between IRF5 polymorphisms and autoimmune diseases: a meta-analysis. Genet Mol Res. 2014;16;13(2):4473-85. (*Co-first Author; IF=0.850) 

9.Liang Tang, Honggang Lin, Bifeng Chen: Association of IL4 promoter polymorphisms with asthma: A meta-analysis. Genet Mol Res. 2014; 13(1):1383-1394. (Corresponding author; IF=0.850) 

10. Bifeng Chen, Tao Gu, Bo Ma, Guoqing Zheng, Bingxiong Ke, Xiufeng Zhang, Lirui Zhang, Yuanyuan Wang, Liping Hu, Yang Chen, Jianbo Qiu, Shengjie Nie: The CRHR1 gene contributes to genetic susceptibility of aggressive behavior towards others in Chinese Southwest Han population. Journal of molecular neuroscience. 2013; 52(4):481-486. (IF=2.757) 


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